Anthony Adams (Luke Wilson) has finally been released from a mental institution he had been placed in after he had a nervous breakdown. Soon after, his old buddy Dignan (Owen Wilson) finds him and gets him involved in a devious plan to go on a crime spree with a former boss named Mr. Henry. A little ways down the line they receive help from a friend named Bob Mapplethorpe (Robert Musgrave) and they commit their first crime. They begin to start their journey to the legendary Mr. Henry and along the way Anthony meets a beautiful hotel maid named Ines (Lumi Cavazos) who makes her way into his heart. Once they meet up with Henry, things turn out to be more than they bargained for.